Role of noscomial infection informatics surveillance system in the prevention and control of multidrug-resistant organisms infections

OBJECTIVE: To analyze the role of nosocomial infection informatics surveillance system in the prevention and control of multidrug-resistant organisms(MDROs) infections. METHODS: The First Affiliated Hospital of Guangdong Pharmaceutical University was selected as the study subjects, which had adopted the nosocomial infection informatics surveillance system since Jan.2020. The period of Jan.to Dec.2020 were regarded as the study period, and Jan.to Dec.2019 were regarded as the control period. The situation of nosocomial infection and MDROs infections in the two periods were retrospectively analyzed. RESULTS: The incidence of nosocomial infections and underreporting of nosocomial infection cases in this hospital during the study period were 2.52%(1 325/52 624) and 1.74%(23/1 325), respectively, and the incidences of ventilator associated pneumonia(VAP), catheter related bloodstream infection(CRBSI), catheter related urinary tract infection(CAUTI)were 4.10(31/7 568), 2.11(14/6 634), and 2.50(25/9 993) respectively, which were lower than those during the control period(P< 0.05). The positive rate of pathogenic examination in the hospital during the study period was 77.95%(1 269/1 628), which was higher than that during the control period(P<0.05), the overall detection rate of MDROs was 15.77%(206/1 306), the detection rates of MDROs in Escherichia coli, Acinetobacter baumannii, Klebsiella pneumoniae, Staphylococcus epidermidis, Pseudomonas aeruginosa and Staphylococcus aureus were lower than those during the control period(P<0.05). CONCLUSION: The development and application of the informatics technology-based surveillance system of nosocomial infection could effectively reduce the incidence of nosocomial infections and device related infections, decrease the under-reporting of infection cases, and also reduce the detection rate of MDROs as well as the proportion of MDROs detected in common pathogenic species.

Process assessment of fencing coaches and referees within the scope of the COVID-19 normalization steps

The objective of this study is to measure and construe the opinions of the coaches and referees who are actively participating in fencing competitions in our country and who are licensed by the Turkish Fencing Federation (TFF) for the year of 2020, regarding the organizations to be planned and the issues to be paid attention, within the scope of the Covid-19 normalization steps. An online data collection form was used as a data collection tool in this study, which was structured through the qualitative research method. In the analysis process of the data obtained, the data analysis program called MAXQDA was used. While closed-ended questions were summarized by indicating percentages, the content analysis method was used in the process of analyzing open-ended question and answer reports. The data obtained were visualized with the help of frequency tables and code maps. Finally, some of the opinions of the participants, which were coded, were directly conveyed by interpreting the findings obtained through the tables and code maps. It was determined as a result of the study that the Covid-19 pandemic that poses impacts on the entire world affects the attitudes of fencing coaches and referees to participate in organizations. In the activities planned to be organized, the sub-codes like attending without an audience, open-air competitions, provision of spaciousness and ventilation means in the selection of a competition hall, and risk approval notification are classified.

The impact of COVID-19 on the indicators of the oncological service for breast cancer in Kazakhstan

Introduction. According to International Agency for Research on Cancer in 2040, about 3 million new cases of breast cancer (BC) are predicted and about 1 million women are expected to die from this pathology. The aim of the study to assess the impact of COVID-19 on the indicators of the oncological service for breast cancer in Kazakhstan. Material and research methods. The main method was a retrospective study using descriptive, analytical methods of biomedical statistics and data of the Ministry of Health of the Republic of Kazakhstan - form No.7 and 35 regarding BC (ICD 10 - C50) for 2011-2020. Results. For 2011-2020 42,376 new cases of BC and 12,914 deaths from this pathology were registered. The average annual crude incidence rate was 46.4+or-1.10/0000 (95%CI=44.3-48.5), and increased from 40.8+or-0.70/0000 (2011) to 51 .3+or-0.70/0000 in 2019 and then decrease to 44.2+or-0.70/0000 in 2020 (p<0.001). In dynamics, mortality rates tended to (p<0.001) decrease from 16.1+or-0.40/0000 (2009) to 11.9+or-0.40/0000 in 2019 and 11.5+or- 0.40/0000 in 2020, and the average annual crude mortality rate was 14.2+or-0.60/0000 (95%CI=13.1-15.3). Indicators of early diagnosis (stage I-II) improved from 73.4% (2011) to 86.9% in 2019, and decreased to 84.2% in 2020. Proportion of patients with stage III decreased (from 20.9% in 2011 to 8.4% in 2019 and to 10.0% in 2020) and stage IV (from 5.6% to 4.2% and 5.0%, respectively), i.e. neglect rates are declining. The indicators of morphological verification improved from 95.7% to 99.4% over the years. Conclusions. As a result of the analysis, an improvement in the indicators of morphological verification, early diagnosis, a decrease in the neglect and mortality rates were established. The trends in 2011-2019 differed significantly from the period from 2011-2020, which is due to the COVID-19 pandemic on the registration of BC.

Human factors analysis and risk assessment during the spread of the COVID-19 epidemic: a case study of the 2019 Wuhan outbreak in China

Since the discovery of novel coronavirus pneumonia (Covid-19) in Wuhan, China, in December 2019, it has spread to other Chinese provinces and continents in just one month, becoming a "public health emergency of international concern". The undesired behaviors of the public and patients during the Covid-19 epidemic cannot be ignored, but few scholars have studied them. In this study, we firstly adopted a qualitative analysis method based on a theoretical paradigm to to summarize the human factors in the spread of the COVID-19 epidemic, and defined the concept of "human factors of the epidemic". Then, we analyzed the distribution characteristics of "human factors of epidemic" at each stage by using statistical analysis, and constructed a human factors model of epidemic evolution. Finally, a multi-subject risk assessment model was constructed using a fuzzy Bayesian network analysis method to quantify the human factors risk in the spread of the COVID-19 epidemic. The results of the study are as follows. (1) The human factors of the COVID-19 epidemic mainly focused on five aspects, including cognitive bias, defective design, management bias, environmental defects, and intentional violations. (2) There were differences in the human factors at different stages of the spread of the COVID-19 epidemic. In the outbreak stage, human factors of the COVID-19 epidemic showed complex trends, with factors such as lack of knowledge and low awareness still prevailing on the one hand, and factors such as lack of capacity, overtly agree but covertly oppose, dereliction of duty, concealment and misreporting, lack of resources, protection defects, design defects, escape/fleeing, and public gathering on the other hand also being more prominent. (3) The risk of the spread of the COVID-19 epidemic due to undesired human factors in the subjects involved was high (p=0.641) under conventional intervention scenarios. Risk factors such as low awareness, poor decision making, lack of resources, lack of awareness, system deficiencies, public agglomeration, inadequate protection, misreporting, and dereliction of duty had relatively large sensitivity factors and were key human factors for the spread of the epidemic in Wuhan. Finally, targeted recommendations are proposed based on the evolutionary pattern and risk level of the human factors of the COVID-19 epidemic.

Improving the timeliness of health expenditure tracking in OECD and low-and middle-income countries

The COVID-19 pandemic has highlighted that access to timely health spending data is crucial for informed policy-making. This Health Working Paper summarises and compares the methodologies applied in around half of OECD countries to estimate public and private health spending for the most recent year (i.e. t-1) as well as the approaches taken by the OECD Secretariat to fill existing data gaps for the remaining OECD countries. For the first time, the paper also explores the feasibility of nowcasting health spending for the current year (i.e. t) and examines data sources that could be potentially useful in such an exercise. While this review should help OECD countries that do not yet have experience in estimating health spending for year t-1 to improve the timeliness in their data reporting, a special focus in this paper lies on testing the applicability of the methods in low- and middle-income countries (LMIC), using the WHO Western Pacific Region (WPRO) as an example. Generally, different data sources exist in many countries that would allow for a more timely estimation for health spending aggregates.

Study of the problems and prospects of small tourism business development in the city of Almaty

This study is based on an understanding of the state of development of small tourism businesses in Almaty, one of the oldest settlements located along the Great Silk Road. The aim of the study was to obtain accurate data on the current state of development of small tourism businesses in Almaty and to identify problems and prospects. In the course of the research, 655 questionnaire responses from business owners and managers meeting the selection criteria were selected and rigorously monitored over a period of 3 months. As a result of the study, the most important problems of small tourism businesses in Almaty were identified, which include: 75.7% of respondents lacked knowledge about tourism activities;53.6% of entrepreneurs do not conclude contracts with employees;82% of business representatives do not have marketing plans;and, as a consequence, inability to obtain loans from banks;and the consequences of the war in Ukraine. However, we also saw some positive trends in the survey: the willingness of respondents to overcome the consequences and the crisis of the covid pandemic-19;motivation to develop their own business;28.7% of young entrepreneurs;74.7% of individual entrepreneurs invest in small tourism businesses. Thus, this study is an auxiliary tool for solving the problem of sustainable development of tourism infrastructure of Almaty, service activities, problems arising in small tourism business.

Fumbling out the effective pathways to apply the wildlife and forest analytic toolkit in the Mekong region: looking at data and analysis perspectives

The Wildlife and Forest Analytic Toolkit, introduced by the International Consortium on Combating Wildlife Crime (ICCWC), is designed to increase the effectiveness of measures combating wildlife and forest crimes (WAFCs). Greater Mekong Subregion (GMS) countries have applied this toolkit as one of their priority actions after recognizing concerns about the biodiversity system and conservational zone through several illegal wildlife trade (IWT) activities. Although the toolkit has realized its fundamental objectives to readjust legal frameworks, enhance enforcement involvement, and improve their judicial and prosecutorial operations, the last components of data and analysis have not yet been implemented. This leads to slow updates of both trends and patterns concerning WAFCs that raise questions about the real levels of exploitation in the region. Using gray literature with published materials, combined with the IWT's database in the CITES system, this study examines why the data and analysis component of the Toolkit created obstacles in the GMS countries. Findings point to there being at least four main challenges to implementing data and analysis as the toolkit has recommended in the region: (1) availability and reliability of data;(2) data collection;(3) data resources (internal vs. external level);and (4) analytic research and its related monitors. Some practical recommendations call for further discussions. Meanwhile, updated information and specific data relating to zoonotic disease transmission are timely, considering the coronavirus pandemic.

Possibilities of increasing the efficiency of modern advertising means in electronic trade

The article discusses the possibilities of increasing the effectiveness of advertising means in modern electronic trade. The demand for modern advertising means has increased in Georgia, and the increase in the effectiveness of their use will help the development of electronic commerce in Georgia. The purpose of the study is to determine the prospects for the development of e-commerce in Georgia in the post-covid period, to study the possibilities of modern advertising means in this field, and to determine the ways of their implementation. Methods of collecting, grouping, and analyzing materials about electronic commerce were used in the development of the paper. The method of data collection is mainly used in the electronic trade system of Georgia, on the basis of which the possibilities of using modern advertising means in this field were identified and recommendations for their implementation were developed. In order to increase the competitiveness of the food and nutrition products produced in Georgia, it is necessary to improve the connections between the separate links of their production, to synchronize the production processes. In order to increase the level of food self-sufficiency of Georgia, it is necessary to protect the production of import-substituting, domestic, agrarian products with non-tariff barriers, and to properly manage their production and logistics. Significant and rapid changes in the global supply chain of food and nutrition products provoked by the Covid-19 pandemic have become an opportunity to increase the level of food self-sufficiency of Georgia, which needs to be properly used.

Summary of global surveillance data of infectious diseases in December 2022

In December 2022, a total of 68 infectious diseases were reported globally, affecting 235 countries and regions. Except for influenza, the top five infectious diseases affecting greatest number of countries and regions were COVID-19 (235), monkeypox (110), dengue fever (28), measles (27) and cholera (14). The top five infectious diseases with highest case fatality rates were Ebola virus disease (47.0%), Rift Valley fever (44.2%), Crimean-Congo haemorrhagic fever (40.0%), Lassa fever (17.6%) and West Nile fever (7.6%). The top five infectious diseases with greatest number of deaths were COVID-19, malaria, cholera, dengue fever and measles. The prevalent infectious diseases in Asia were COVID-19, cholera and dengue fever, the prevalent infectious diseases in Africa were COVID-19, cholera, yellow fever, Lassa fever, monkeypox, malaria and measles, the prevalent infectious diseases in America were COVID-19, cholera, monkeypox, dengue fever and chikungunya fever, the prevalent infectious disease in Europe were COVID-19, monkeypox and invasive group A streptococcus infection.

Risk assessment of global Coronavirus disease 2019 pandemic in December 2022

Objective: To assess the global epidemic of Coronavirus disease 2019 (COVID-19) in December 2022 and the risk of importation. Methods: According to the daily COVID-19 data publicly released by Johns Hopkins University, combined with the policy stringency index published by the University of Oxford, an epidemiological description method was used to provide a comprehensive and timely assessment of the global epidemiological risk overview, a comprehensive assessment of the epidemic trends in each continent and key countries, as well as a comprehensive analysis of the epidemic and prevention and control policies in 14 neighboring countries. The assessment results for each country are expressed as countries of gl, "countries of the general concern in each continent" and "neighboring countries of special concern". Results: Compared with the previous month, the number of confirmed cases and deaths respectively increased by 38.92% and 25.95% globally in February 2022. Daily new confirmed cases and deaths in the Asia continued to rise in December. The time taken for every new 50 mill confirmed cases and 50 thousand deaths globally has increased significantly. Japan, Korea, America and France were countries with global concern. Brazil, Argentina, Mexico, Mauritius and Australia were the countries of general concern in each continent. Russia with was the special count among the 14 neighboring countries. Conclusion: The global daily new confirmed cases and deaths showed a downward trend after mid-December, but the epidemic situation was prominent in some regions and countries. information and provide timely warnings.

Disparities in COVID-19 case counts and incidence in Florida by race and ethnicity at the county and state level

Background: In 2020, as COVID-19 spread across the United States, reports of disparities in COVID-19 incidence and mortality by race and ethnicity soon followed. This study assessed COVID-19 case counts and incidence by race and ethnicity at county and state levels focusing on Florida. Methods: Counts of COVID-19 were collected from June through December 2020. Chi square analyses assessed disparities in case distribution and linear regressions assessed disparities in incidence and potential interaction between predictors. Results: Race and ethnicity were significant predictors of COVID-19 incidence. Mean incidence was 4.9, 6.6, and 14.3 per 1,000 people among White, Black, and Other populations and 10.9 and 5.0 per 1,000 people among Hispanic and non-Hispanic populations. Incidence was greatest among the Other population (P=0.3825), and greater among Hispanic than non-Hispanic populations (P=0.0057). Conclusion: This study illustrates the disproportionate impact of COVID-19 upon racial and ethnic minorities and highlights the need to improve race and ethnicity data collection in disease reporting.

Cholera, 2021

This report highlights the challenges faced by the global health community in managing cholera outbreaks during the ongoing COVID-19 pandemic and in areas with humanitarian crises and large population movements. In 2021, cholera outbreaks surged, particularly in West Africa, while preventive measures to control COVID-19, such as handwashing and social distancing, may have reduced cholera transmission. However, the pandemic's impact on healthcare access, laboratory capacity, and disease reporting systems, especially in crisis-affected regions, hindered cholera response capacity. Despite efforts to support vulnerable populations and reduce cholera transmission, climate events, and population displacement continued to expose susceptible communities. Globally, 90 countries reported data on cholera, with 35 countries reporting 223,370 cases and 4159 deaths, representing a 30% decrease in reported cases from 2020 but a significant increase in the number of deaths. Nigeria accounted for 50% of reported cases and had the highest number of deaths. Laboratory confirmation of suspected cholera cases remains a priority, and strategic, systematic testing by rapid diagnostic tests should be increased to meet the goals of the global roadmap to end cholera. The collection of demographic information, including age and gender, is also essential to target response measures accordingly.

Prioritization of COVID-19 patients for admission in the intensive care unit in the context of hospital bed shortages: an integrated multi-criteria decision making approach

Background: When an epidemic occurs, resources, including hospital beds, are severely limited and not all patients can be treated;so, hospital bed rationing is inevitable. Therefore, the aim of this study is to provide a method for evaluating and prioritizing patients with COVID-19 for admission to the intensive care unit. Methods: This was a descriptive-survey study in terms of data collection method conducted in the summer of 2021. Following the formation of an expert panel with 4 specialists, a three-stage approach to evaluating and prioritizing COVID-19 patients was adopted by combining multi-criteria decision analysis methods. In the first stage, effective criteria and sub-criteria for patients' prioritization were identified by a panel of experts and related studies, and the hierarchy of criteria was drawn. In the second stage, the Fuzzy best-worst method was used to determine the weight of criteria and sub-criteria. Finally, in the third stage, a combined compromise solution method was performed to prioritize 10 patients in need of COVID-19 and the most critical patient was selected. Results: According to the experts, among the 15 criteria studied, respiratory rate, PaO2/FiO2, impaired consciousness, mean arterial pressure and age were identified as 5 of the most important criteria in prioritizing COVID-19 patients for intensive care unit admission. In addition, 10 COVID-19 patients referred to Shohadaye Pakdasht Hospital were evaluated and prioritized with the proposed approach. Conclusion: The proposed method can be used as a useful tool in the evaluation of COVID-19 patients for admission to the intensive care unit and to support the vital decisions of physicians.

COVID-19 as a factor in accelerating the automation of port logistics processes in the port of Callao - Peru

The purpose of this study was to analyze the impetus that the pandemic caused by the new Covid-19 coronavirus will provide to the acceleration of the automation of the Port Logistics processes in the Port of Callao in Peru. The study was carried out from a qualitative approach, using the conceptual - inductive and phenomenological method as specific methods. Likewise, to collect the information, the in-depth interview technique applied to six specialists involved with the Port of Callao and its different operations was used. The information collected from the informants was developed through the synthesis and the Atlas.ti software. Regarding the investigative findings and conclusions, the pandemic has changed the way of conducting international business around the world, and a gap has opened in relation to the use of social networks, the internet and the tools that it brings with it. have become indispensable for this economic area, and also for the processes of exporting and importing goods and services, in the same way, to stop contagion and the spread of the virus, the governments of each country have adopted measures that have affected both producers as well as consumers.

Descriptive analysis of the COVID-19 pandemic during the first and second waves in a North-Central State in Nigeria

Introduction: COVID-19 is a novel infection caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2). This study was a descriptive analysis of COVID-19 during the first and second waves in Kwara State, North-Central Nigeria.

The utilization of 'Jogja Pass' mobile application as an effort to prevent the spread of COVID-19 in Special Region of Yogyakarta

In order to respond to the increasing number of COVID-19 cases, the government created the Jogja Pass mobile application for screening and tracing as well as supporting the implementation of smart city in Special Region of Yogyakarta. This study aims to identify the utilization of the Jogja Pass, analyze the impact of the Jogja Pass in handling COVID-19, and identify obstacles in the utilization of the Jogja Pass for the application development purposes. This study employed quantitative descriptive and qualitative descriptive methods. The primary data were obtained from in-depth interviews with relevant institutions and through questionnaires to the public. The secondary data were obtained through recapitulation of application data. The results indicated that the users of the Jogja Pass are spread throughout the region of Yogyakarta and it is used at 113 public area points. The Jogja Pass has positive impact on the users and becomes one of the SOPs for health protocols in several public areas. The obstacles in the development of the Jogja Pass include limited human resources and funds, dishonesty of users in filling out the screening test, and the Jogja Pass has been taken down from the Android Play Store.

Routine vaccination coverage - worldwide, 2020

This report, which updates previous reports, presents estimates of global, regional, and national vaccination coverage and trends as of 2020. It describes the changes in vaccination coverage and the numbers of unvaccinated and undervaccinated children as measured by receipt of the first and third doses of diphtheria, tetanus, and pertussis-containing vaccine (DTP)in 2020, when the COVID-19 pandemic began, compared with 2019. Global coverage estimates with the third dose of DTP (DTP3) and a polio vaccine (Pol3) fell from 86% in 2019 to 83% in 2020. Similarly, MCV1 coverage fell from 86% in 2019 to 84% in 2020. The last year the coverage estimates were at 2020 levels was 2009 for DTP3 and 2014 for both MCV1 and the third dose of Pol (Pol3). Worldwide, 22.7 million children(17% of the target population) did not receive DTP in 2020, compared with 19.0 million (14%) in 2019. Children who did not receive the first DTP dose (DTP1) by age 12 months (zero-dose children) accounted for 95%of the increased number. Among those who did not receive DTP3 in 2020, approximately 17.1 million (75%)were zero-dose children. Global coverage decreased in 2020 compared with 2019 estimates for the completion of Haemophilus influenzae type b (Hib), hepatitis B vaccine (HepB), human papillomavirus vaccine (HPV),and rubella-containing vaccine (RCV). To reach full coverage with all recommended vaccines, tailored strategies will be needed, especially to reach communities with a lot of children who haven't had any or enough vaccines.

Cholera, 2020

This article provides a summary of the 2020 report of the global cholera surveillance and how the COVID-19 pandemic affected cholera detection and case counting. Overall, in 2020, 80 countries reported data on cholera to WHO. Of these, 27 countries reported a total of 323,320 cholera cases and 857 deaths, for a case-fatality rate(CFR) of 0.27%, while 53 countries reported 0 cases for the year (Table 2). After the exclusion of Yemen, which accounted for 85%of cases reported globally to WHO for2020, 47,608 cases and 742 deaths (CFR, 1.5%) were reported from other countries.

Summary of global surveillance data of infectious diseases in March 2022

In March 2022, a total of 63 infectious diseases were reported globally, affecting 230 countries and regions. Except for influenza, the top five infectious diseases affecting greatest number of countries and regions were COVID-19 (230), dengue fever (32), measles (29), chikungunya fever (10) and cholera (9). The top five infectious diseases with highest case fatality rates were Crimean-Congo haemorrhagic fever (33.3%), Rift Valley fever (20.0%), Lassa fever (18.6%), yellow fever (11.3%) and monkeypox (5.5%). The top five infectious diseases with greatest number of deaths were COVID-19, malaria, measles, cholera and Lassa fever. The prevalent infectious diseases in Asia were COVID-19 and dengue fever, the prevalent infectious diseases in Africa were COVID-19, cholera, yellow fever, Lassa fever, malaria, measles and poliomyelitis, the prevalent infectious diseases in America were COVID-19, dengue fever and chikungunya fever, the prevalent infectious disease in Europe was COVID-19.

Risk assessment of public health emergencies concerned in the mainland of China, April 2022

Objective To assess the risk of public health emergencies, both the indigenous ones and the imported ones, which might occur in the mainland of China in April 2022. Methods An internet based expert counsel was conducted to analyze the surveillance data of public health emergencies and priority communicable diseases in China reported through different channels, and the experts in all provincial centers for disease control and prevention attended this video conference. Results It is expected that number of domestically reported public health emergency events other than COVID-19 in April would remain unchanged from March. The risk of domestic COVID-19 outbreaks caused by the indigenous transmission and the foreign importation is high, making it more difficult to prevent and control the epidemic. Local governments need to strengthen epidemic prevention and control in accordance with national requirements and hold the bottom line of no large-scale rebound of the epidemic. The number of pertussis cases will maintain rising trend due to the improvement of laboratory testing technology, the weakening of vaccine protection and the strengthening of surveillance in some districts. Conclusion Special attention should be paid to COVID-19. General attentions should be paid to pertussis.